Mycobacterium Ulcerans diagnosis and management

7月 6, 2010 · Posted in 未分類 

M. ulcerans causes chronic ulceration, usually on an exposed area of the body, often the lower limbs. The condition has a wide distribution in the tropics and is often called Buruli ulcer. The pathogenesis of M. ulcerans disease is related to its unique ability to produce a tissuedamaging toxin, mycolactone, recently characterized as a macrolide molecule which causes cell death by apoptosis.

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